Ef®ciency considerations in the additive hazards model with current status data
نویسنده
چکیده
For current status data, LIN, OAKES and YING (1998) proposed a procedure for estimation of the regression parameters in the additive hazards model that makes clever use of martingale theory. However, one of the outstanding problems posed in the paper was the issue of ef®cient estimation, as their estimators do not attain the semiparametric information bound. In this paper, we explore this issue and provide a characterization of the NPMLE. We conduct ef®ciency comparisons between the NPMLE and the procedure of LIN et al. (1998) analytically and numerically through analysis of a dataset from a tumorigenicity experiment.
منابع مشابه
Synthesis of Polypyrrole/CeO2 Nanocomposite and its Application for Improving the Corrosion Protection of Acrylic Waterborne Coating on Mild Steel
In this work, polypyrrole/CeO2 nanocomposite (NC) was synthesized in the presence of methylorange as a reactive self-degraded soft template. The field emission scanning electron microscopy(FESEM) images indicate that the CeO2 NPs have a nucleus effect and cause a homogenous PPycore–shell type morphology with an encapsulation of the CeO2 core by the PPy shell. The effect ofNC on acrylic waterbor...
متن کاملEfficient Estimation of the Partly Linear Additive Hazards Model with Current Status Data
This paper focuses on efficient estimation, optimal rates of convergence and effective algorithms in the partly linear additive hazards regression model with current status data. We use polynomial splines to estimate both cumulative baseline hazard function with monotonicity constraint and nonparametric regression functions with no such constraint. We propose a simultaneous sieve maximum likeli...
متن کاملHidden hazards and dangers associated with the use of HME/filters in breathing circuits. Their effect on toxic metabolite production, pulse oximetry and airway resistance.
Current airway dust ®lter technology emanates from the USA mining industry during the 1930s. It was further developed and improved by the USA military during World War II to prevent workers from inhaling very ®ne radioactive particles in the nuclear industry. These later ®lters we now recognize as high ef®ciency particulate air ®lters (HEPA). The ef®ciency of ®lters varies according to the numb...
متن کاملBayesian model selection and averaging in additive and proportional hazards models.
Although Cox proportional hazards regression is the default analysis for time to event data, there is typically uncertainty about whether the effects of a predictor are more appropriately characterized by a multiplicative or additive model. To accommodate this uncertainty, we place a model selection prior on the coefficients in an additive-multiplicative hazards model. This prior assigns positi...
متن کاملIT Worskhop on Detection Estimation Classi cation and Imaging Santa Fe NM USA Feb Optimum Multiuser Asymptotic E ciency of CDMA with Random Spreading
This paper analyzes the hign SNR performance of optimum multiuser detectors for synchronous direct sequence spread spectrum with random spreading in an additive white Gaussian noise channel We show that the asymptotic ef ciency of a K user system with spreading gain N converges to almost surely as K and N go to in nity and K N is kept equal to an arbitrary con stant
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2001